Doing keto long enough however, your kidneys might wear out before your brain
I initially tried keto just to lose weight. But to my surprise, after about three weeks, I started feeling much clearer mentally, and overall just lighter, like something had lifted.
Back then, I thought it was just a coincidence. Now, reading this paper, I’m starting to think it might really have something to do with how the brain gets its energy.
I'm not sure I understand the method.
Is it correct that the study looked at the effect of a single (large) dose of ketones, rather than ongoing consumption?
As I understand it, dosage was 0.395g per kilo of body weight (so about 27g for 70kg subject), and that was it - with measurements of brain activity before and after.
No indication of duration of effect?
I Googled and have found a product on Amazon, which is asking about 30 USD for that dose, which would make daily 900 USD a month (!)
What are those supplements as I find a keto diet impossible to maintain.
Absolutely terrible science, the conclusion is a bunch of mechanistic speculation passed off as causal inference, just more keto bro grifters trying to pretend to be scientists.
Can someone give me a TL;DR?
You can also get ketones in nail polish removers.
“Ketones, whether produced endogenously through fasting or low-carbohydrate/high-fat diets or administered exogenously as a supplement, have been shown to improve age-related cognitive decline (23–25) and to restore insulin-resistance-induced deficits in axonal conduction velocity” - Another win for the gym bros
Of note from the "Acknowledgements" section:
> K.C. is a director of TdeltaS Ltd., a company spun out of the University of Oxford to develop products based on the science of ketone bodies in human nutrition.